How working Eribulin Mesylate - it - 100359


How working Eribulin Mesylate - it

Description: The mesylate salt of a synthetic analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. Eribulin binds to the vinca domain of tubulin and inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression
Shared By : raffaelegiusti
Posted on : 12/18/11
Added : 7 years ago
Category : General

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