How Does This Affect Clinicians Today?

How Does This Affect Clinicians Today?

Cancer-News

4 weeks
4 Views
Share
Want to watch this again later?
Sign in to add this video to a playlist. Login
0 0
Category:
Description:

Zhibo Ma, PhD of @salkinstitute explains how this affects treatment and clinicians today.

__________

Breast cancer is one of the most common cancers, and some types are among the hardest to treat. The different types and presence of many different cells makes it difficult to target these tumors. Scientists at the Salk Institute have now used state-of - the-art technology to test each cell during normal breast development to understand what happens wrongly in cancer.

The results of the group, published in the Cell Reports on 8 October 2019 and distributed in a free online resource, lay the foundations for understanding normal breast growth and can lead to new strategies for tumor control.

"In order to understand what goes wrong in breast cancer, we need to first understand how normal development works," says Geoffrey Wahl, a professor in the Gene Expression Laboratory and senior author of the paper. "This study represents a major step in that direction, as we were able to profile each cell during breast development. We expect this information to be a valuable hypothesis-generating resource for the mammary gland community."

Two major cell types that are often implicated in breast cancer are found in mature breast tissue, luminary cells and basal cells. Luminal cells line the ducts and make milk while basal cells around the ducts contract to extract milk. The scientists were interested in what drives the molecular changes that control how stem cells become specialized in these cell types during growth. In particular, they explored how DNA packaging inside the cell, known as chromatin, could make certain genes accessible or unavailable to influence gene expression and growth.

Read here: https://www.oncologytube.com/video/mapping-the-usual-breast-development-to-recognize-cancer-better

Up Next Autoplay
Who is Eligible for the AVIATOR Study? @SeattleCCA
Who is Eligible for the AVIATOR Study? @SeattleCCA
Category: Breast Cancer
1 Views
SeattleCCA 15 hours
The AVIATOR Study @SeattleCCA
The AVIATOR Study @SeattleCCA
Category: Breast Cancer
0 Views
SeattleCCA 15 hours
Roswell Park Breast Surgery Chief Gives Keynote Talk on Immunotherapy for Breast Cancer
Roswell Park Breast Surgery Chief Gives Keynote Talk on Immunotherapy for Breast Cancer
Category: Breast Cancer
6 Views
Roswell Park 1 week
Biomarkers with Locally Advanced Metastatic Carcinoma Results
Biomarkers with Locally Advanced Metastatic Carcinoma Results
Category: Breast Cancer
2 Views
UChicago Medicine 3 weeks
Biomarkers in Urothelial Carcinoma
Biomarkers in Urothelial Carcinoma
Category: Breast Cancer
27 Views
UChicago Medicine 3 weeks
Trends in Breast Cancer Death Rates
Trends in Breast Cancer Death Rates
Category: Breast Cancer
1 Views
Cancer-News 3 weeks
Breast Cancer Trends in U.S.
Breast Cancer Trends in U.S.
Category: Breast Cancer
11 Views
Cancer-News 3 weeks
Lower Costs in Breast Cancer: How This Affects Treatment
Lower Costs in Breast Cancer: How This Affects Treatment
Category: Breast Cancer
2 Views
ONeal Comprehensive Cancer Center 3 weeks
Lower Costs for Patients in Metastatic Breast Cancer
Lower Costs for Patients in Metastatic Breast Cancer
Category: Breast Cancer
28 Views
ONeal Comprehensive Cancer Center 4 weeks
Using Technology to Better Understand What Goes Wrong in Cancer
Using Technology to Better Understand What Goes Wrong in Cancer
Category: Breast Cancer
18 Views
Cancer-News 4 weeks