Karen Mustian, PhD, MPH, ACSM of the University of Rochester Medical Center, Rochester, New York, NY, discusses advantages of using yoga as part of an exercise routine. Dr Mustians clinical trial showed yogas efficacy in improving sleep quality, insomnia, fatigue, and quality of life. In addition, Dr Mustians studies showed an improvement in regulation of patients circadian rhythm. Disruption in circardian rhythm is associated with disruptions in immune responses and inflammation, as well as sleep. Yoga helps to regulate the cancer survivors circadian rhythm, leading to improvements in sleep quality, insomnia, and fatigue. Recorded at the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of Ocular Oncology (ISOO) 2016 Annual Meeting on Supportive Care in Cancer held in Adelaide, Australia.