Peter Hillmen, MD, PhD from St. James' University Hospital, Leeds, UK discusses the debate 'Can we cure CLL today?' held at the European Hematology Association (EHA) 2016 Annual Congress in Copenhagen, Denmark. According to Prof Hillmen, the key question is how to define cure. He also discusses minimal residual disease (MRD) and the difference between measurable and unmeasurbale MRD. Prof Hillmen argues that it is unlikely that many or any patients are being cured at the moment even though some patients may never relapse.