Stephan Grupp, MD, PhD from Children's Hospital of Philadelphia, Philadelphia, PA outlines his work at the University of Pennsylvania. Currently his team is investigating the characteristics of T-cells and how they work in treatment, with the hope of answering such questions: Can we predict patients who are going to do well? Can we understand what the requirements are for the collected T-cells? Can we extend this to areas outside of leukemia? Recorded at the European Hematology Association (EHA) 2016 Annual Congress in Copenhagen, Denmark.