How does it differ from previously published nomograms?

How does it differ from previously published nomograms?

Cleveland Clinic

2 months
1 Views
Share
Want to watch this again later?
Sign in to add this video to a playlist. Login
0 0
Category:
Description:

Shauna Campbell, MD of Cleveland Clinic answers a question received from colleagues: how does it differ from previously published nomograms?

_______

The integration of prostate-specific antigen (PSA) kinetics into a nomogram widely used to predict outcomes of salvage therapy offers physicians and patients a more nuanced, longer-term look at prostate cancer-specific outcomes.

In 2007, a multi-institutional cohort led by Cleveland Clinic’s Glickman Urological and Kidney Institute developed a nomogram to predict prostate cancer-specific and all-cause mortality at six years after salvage radiotherapy (SRT).

Almost a decade later, a study led by Cleveland Clinic Cancer Center radiation oncologist Rahul D. Tendulkar, MD, updated the nomogram with evidence that early initiation of SRT following radical prostatectomy (RP) reduced biochemical failure (BF) and distant metastases (DM).

The researchers’ most recent update to the nomogram was presented at the 2019 annual meeting of the American Society for Radiation Oncology (ASTRO).

“One critique of our previous update was the lack of PSA kinetics among the predictive factors,” says Shauna Campbell, DO, chief resident, radiation oncology, Cleveland Clinic. “This version of the nomogram adds initial postoperative PSA level and PSA doubling time [PSADT] to the picture.”

Read the rest here: https://consultqd.clevelandclinic.org/postprostatectomy-prostate-specific-antigen-kinetics-associated-with-recurrence-after-salvage-radiation/

Up Next Autoplay
How does this affect treatment?
How does this affect treatment?
Category: Colorectal Cancer
8 Views
Cleveland Clinic 2 months
Is this truly safe?
Is this truly safe?
Category: Colorectal Cancer
2 Views
Cleveland Clinic 2 months
Radiation Therapy in Patients with Inflammatory Bowel Disease and Rectal Cancer
Radiation Therapy in Patients with Inflammatory Bowel Disease and Rectal Cancer
Category: Colorectal Cancer
12 Views
Cleveland Clinic 2 months
How does this affect clinicians today?
How does this affect clinicians today?
Category: Brain Cancer
5 Views
Cleveland Clinic 2 months
Targeting Metabolic Reprogramming to Radiosensitize Glioblastoma Stem Cells
Targeting Metabolic Reprogramming to Radiosensitize Glioblastoma Stem Cells
Category: Brain Cancer
13 Views
Cleveland Clinic 2 months
Nomograms on salvage radiotherapy
Nomograms on salvage radiotherapy
Category: Pancreatic Cancer
2 Views
Cleveland Clinic 2 months
Impact of Post-Prostatectomy Prostate Specific Antigen (PSA) Kinetics on Outcomes of Salvage Radiotherapy
Impact of Post-Prostatectomy Prostate Specific Antigen (PSA) Kinetics on Outcomes of Salvage Radiotherapy
Category: Prostate Cancer
1,839 Views
Cleveland Clinic 2 months
How this will affect clinicians today
How this will affect clinicians today
Category: Other
3 Views
Cleveland Clinic 2 months
Why Dose Escalation?
Why Dose Escalation?
Category: Other
5 Views
Cleveland Clinic 2 months