Impact of Post-Prostatectomy Prostate Specific Antigen (PSA) Kinetics on Outcomes of Salvage Radiotherapy

Impact of Post-Prostatectomy Prostate Specific Antigen (PSA) Kinetics on Outcomes of Salvage Radiotherapy

Cleveland Clinic

4 weeks
36 Views
Share
Want to watch this again later?
Sign in to add this video to a playlist. Login
0 0
Category:
Description:

Shauna Campbell, MD of Cleveland Clinic explains the impact of post-prostatectomy prostate specific antigen (PSA) kinetics on outcomes of salvage radiotherapy.

_______

The integration of prostate-specific antigen (PSA) kinetics into a nomogram widely used to predict outcomes of salvage therapy offers physicians and patients a more nuanced, longer-term look at prostate cancer-specific outcomes.

In 2007, a multi-institutional cohort led by Cleveland Clinic’s Glickman Urological and Kidney Institute developed a nomogram to predict prostate cancer-specific and all-cause mortality at six years after salvage radiotherapy (SRT).

Almost a decade later, a study led by Cleveland Clinic Cancer Center radiation oncologist Rahul D. Tendulkar, MD, updated the nomogram with evidence that early initiation of SRT following radical prostatectomy (RP) reduced biochemical failure (BF) and distant metastases (DM).

The researchers’ most recent update to the nomogram was presented at the 2019 annual meeting of the American Society for Radiation Oncology (ASTRO).

“One critique of our previous update was the lack of PSA kinetics among the predictive factors,” says Shauna Campbell, DO, chief resident, radiation oncology, Cleveland Clinic. “This version of the nomogram adds initial postoperative PSA level and PSA doubling time [PSADT] to the picture.”

Read the rest here: https://consultqd.clevelandclinic.org/postprostatectomy-prostate-specific-antigen-kinetics-associated-with-recurrence-after-salvage-radiation/

Up Next Autoplay
Measuring Chromatin Accessibility: How Reliable is This Data?
Measuring Chromatin Accessibility: How Reliable is This Data?
Category: Breast Cancer
0 Views
Cancer-News 7 minutes
Dual-function Virus Designed For Killing Tumor Cells and Helping Immune Cells
Dual-function Virus Designed For Killing Tumor Cells and Helping Immune Cells
Category: Melanoma and Skin Cancer
0 Views
Cancer-News 41 minutes
Using Technology to Better Understand What Goes Wrong in Cancer
Using Technology to Better Understand What Goes Wrong in Cancer
Category: Breast Cancer
0 Views
Cancer-News 1 hour
Mapping the usual breast development to recognize cancer better
Mapping the usual breast development to recognize cancer better
Category: Breast Cancer
2 Views
Cancer-News 1 hour
Metformin: How Does This Affect Treatment?
Metformin: How Does This Affect Treatment?
Category: Ovarian Cancer
2 Views
Cancer-News 2 hours
New Frontier Possibility for Preventing Ovarian Cancer
New Frontier Possibility for Preventing Ovarian Cancer
Category: Ovarian Cancer
1 Views
Cancer-News 2 hours
"Wild idea" opens possible new boundaries to ovarian cancer prevention
Category: Ovarian Cancer
3 Views
Cancer-News 2 hours
Personalized Algorithms: How is this different?
Personalized Algorithms: How is this different?
Category: Immunotherapy
4 Views
Cancer-News 22 hours
Algorithm Personalizing Best Targets for Immunotherapy
Algorithm Personalizing Best Targets for Immunotherapy
Category: Immunotherapy
3 Views
Cancer-News 23 hours
Algorithm personalizes the best targets for immunotherapy for cancer mutations.
Algorithm personalizes the best targets for immunotherapy for cancer mutations.
Category: Immunotherapy
5 Views
Cancer-News 23 hours