Multiple Myeloma trial highlights: ARROW, OPTIMISMM & ALCYONE

Multiple Myeloma trial highlights: ARROW, OPTIMISMM & ALCYONE

VJHemOnc

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The 23rd Congress of the European Hematological Association (EHA) 2018 in Stockholm, Sweden, saw many researchers presenting the newest data from their recent clinical trials. In this video, Mohamad Mohty, MD, PhD, of Saint-Antoine Hospital, Paris, France, speaks about his highlights for multiple myeloma (MM), giving a critical overview of the data and their implications for the future of MM care. He includes: ARROW (NCT02412878), which has demonstrated that carfilzomib has a PFS benefit in once-weekly vs. twice-weekly dosing; OPTIMISMM (NCT01734928), which reported a PFS benefit from pomalidomide, bortezomib and dexamethasone in the relapsed/refractory setting; and a sub-group analysis of ALCYONE (NCT02195479), which showed that the quartet therapy of daratumumab plus bortezomib, melphalan and prednisone (VMP) is more effective in elderly patients than VMP alone.
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